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General Discussion

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NREMTP Review-Mike B.🚑🚒 "Endocrine"

Pediatrics

  • Neonates-15 mL/kg

  • Peds-20 ml/kg

  • Adults-20 mL/kg

  • Adults Sepsis-30 ml/kg

  • Epi-0.01 mg/kg

  • Amiodarone-5 mg/kg

  • Defibrillation-2 J/kg, 4 J/kg, 4 J/kg

  • Lidocaine-1 mg/kg


Addisons Disease

  • Hypoadrenalism

  • Low production of glucocorticoids (Cortisol & Cortisone)

  • Low BP-Hypotension

  • Hypoglycemia

  • Low energy

  • Weakness

  • Severe dehydration

  • Bronze discoloration of the skin


Cushing's Disease

  • Hyperadrenalism

  • Hyperglycemia

  • Fluid retention

  • HTN

  • Heavy

  • Purple striae-stretch marks

  • Bruising

  • Poor healing









Endocrine System


Thyroid Gland (Anterior Neck)

  • Regulates metabolism

  • Hormones-T3, T4, Calcitonin




Grave's Disease (Hyperthyroidism)

  • An autoimmune disease

  • Everything is elevated except their weight

  • Tachycardia

  • HTN

  • Fever

  • Heat intolerant

  • Diarrhea

  • Exophthalmos-Bulging eyes






Adrenal Glands (Top of the kidneys)

  • Regulates the sympathetic N.S (Epi & Nor epi)

  • Produces sex hormones (Testosterone & Estrogen)

  • Regulates stress response (Glucocorticoids-Cortisol & Cortisone)

  • Regulates fluid balance & BP (Mineralcorticoids-Aldosterone)


Hormones

  • Epi/Nor-epi

  • Testosterone & Estrogen

  • Cortisol & Cortisone

  • Aldosterone

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Homework

  • Know Thyroid conditions

  • Low (Hypothyroidism, Myxedema coma

  • High (Hyperthyroidism, Grave's Disease, Thyroid storm)

  • Know adrenal conditions (Addison's Disease, Cushing's Disease)



70-110 mg/dl


>120=Hyperglycemia


250-550-Type 1-DKA

600-1200-Type 2-HHS/HHNK/HHNS





Pancreas

  1. Insulin

  2. Glucagon (Hormone)

  3. Somatostatin



What is the MOA of Glucagon?

  • Travels to the liver, to allow it to release glycogen into the bloodstream



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